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The protein was solubilised using n-dodecyl -D-maltoside (DDM) and cholesteryl hemi-succinate (CHS), which was then exchanged for glyco-diosgenin (GDN) during purification

For participants enrolled in a clinical trial , the study team should be the first point of contact for any concerns about the medicine, its preparation, storage, or any symptoms experienced

However, short-term CR disturbs this balance and may switch-on pro-oncogenic pathways

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While the treatment with NP4 alone caused a strong production of ROS, the preincubation with NAC and subsequent treatment with NP4 showed a poor ROS generation (Fig

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