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How Semaglutide Affects the Brain GLP-1 analogs appear to bind to receptors on neurons on some parts of the brain

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From diabetes to longevity Originally developed for type 2 diabetes, GLP-1s are now approved for weight loss and increasingly for other conditions including cardiovascular disease, kidney disease, and sleep apnoea with trials underway for Alzheimers, addiction, and even osteoarthritis

doi:10.1136/bmj.322.7281.290

For employers that include GLP-1s for weight loss, this is expected to translate into higher overall cost exposure

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