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Receptor binding affinity, intrinsic activity, and duration of receptor occupancy all influence downstream signaling

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doi: 10.1038/s41467-023-37368-1 78 SousaGFCarpesRMSilvaCAOPereiraMEPSilvaACVFCoelhoVAGSet al

gallinarum, across the intestinal epithelium of autoimmune-prone hosts has been reported to promote SLE, particularly due to the ability of this bacterium to migrate to immunological hotspots including the mesenteric lymph nodes, liver, and spleen (Manfredo Vieira et al