Store out of reach of children
NICE guidelines (NG28) recommend GLP-1 receptor agonists for type 2 diabetes based on individual patient factors, including cardiovascular risk, and not strictly as second- or third-line therapy after metformin failure
in Spain, its current prevalence ranges between 2833%11,12 and it is a recognized as a cardiovascular risk factor and increases the mortality in this population.1315 Furthermore, in patients with DM2 and advanced CKD there are limitations in the prescription of certain antihyperglycemic drugs (e.g., metformin or sulfonylureas) and there is an increased risk of hypoglycemia with antihyperglycemic treatment,16 a complication that is associated with increased cardiovascular risk17 and hinders the achievement of glycemic control targets
2 Strategic Impact With this expanded label, Novo Nordisk strengthens its leadership in the booming GLP-1 therapeutic class, continuing its competitive race with Eli Lilly and Company
Those expecting the same outcomes as standard doses without acknowledging risk of diminished effect
Some devices require pinching a fold of skin while others do not