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We also demonstrated that ectopic expression of wild-type mTOR, constitutively activate S6K1, or downregulated 4E-BP1 partially prevented rotenone-induced neuronal apoptosis, suggesting that rotenone-induced neuronal loss in PD may be prevented by activating mTOR signalling 15

Some patients transition to a maintenance dose after reaching their goal, while others taper off under clinical supervision

[DOI] [PMC free article] [PubMed] [Google Scholar] 297.Mostowy S

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