In the tiny human trials so far it is well tolerated, but the sample sizes are small and selective (this isnt a good representation of either a)
Patients taking GLP-1 drugs lose weight faster, but they may experience side effects, such as nausea, vomiting, diarrhea, indigestion, fatigue, dizziness, and hypoglycemia, along with other potential adverse events
Others reach 2.4mg and find the side effects too burdensome, stepping back down to 1.7mg for a better balance between efficacy and tolerability
PMID: 11533304
Because the original research concerned the gut, PLIVA tested it in the bowel disease ulcerative colitis, given as an enema, in a randomized, placebo-controlled study [11]
Always use the semaglutide dosage calculator to verify your specific concentration before injecting