How to Choose What to Address First There is no single right answer, but starting with your goal, then looking at what the evidence actually supports, gets you further than starting with whichever treatment sounds most interesting
Sant Anna BG, Musolino NRC, Gadelha MR, Marques C, Castro M, Elias PCL, et al
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GLP-1 receptors sit throughout the body, in the brain, pancreas, heart, and blood vessels, and the drugs appear to reduce inflammation and the organ-damaging fat that drives much metabolic harm
DeFronzo recommended several possible combination options for adults with type 2 diabetes: Prior stroke: pioglitazone plus a GLP-1 receptor agonist