Traditionally, both single and combination FDA-approved drugs for obesity have shown moderate, but clinically-important, weight losses (mean weight loss of 3%9% greater than placebo at ~1 year of therapy) (4) (Figure 1)
Contemporary insights identify associations with insulin resistance, type 2 diabetes and a twofold increased risk of cardiovascular disease in excess of that driven by obesity alone
There is no one-size-fits-all dose where weight loss begins, but as your dose increases, you should start to see better results
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