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The beneficial effect of HES on vascular permeability and its relationship with endothelial glycocalyx and intercellular junction after hemorrhagic shock

d) Nitric oxide (NO) release which triggers cGMP pathways

the ratio between them reflects cellular redox status

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Sterile water, by contrast, has no such protection once opened, its generally recommended for immediate, single-use only, with any leftover discarded the same day

For example, while Gln and the Gln-Glu cycle are believed to regulate Glu, an increased cycle turnover could mitigate excessive glutamatergic activity and maintain a balanced excitatory tone [15, 61]