Common side effects include nausea, vomiting, and gastrointestinal discomfort, typically mild and transient
Some men who come in for TRT will also benefit from GLP-1 support
Studies in the Journal of Endocrinology demonstrate that IGF-1 receptor expression in skeletal muscle peaks 6090 minutes after a growth hormone pulse, then declines as negative feedback mechanisms downregulate receptor transcription
Over-the-counter pain relievers like acetaminophen can manage mild injection-site soreness, though most patients find the discomfort minimal with proper technique
Those who follow a vegetarian or vegan diet may have trouble getting enough B12 from food alone
Therefore, it is important that your doctor rule out other possible causes of headache, especially in the absence of history of migraine (Merck Manual 2012