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To be utilized as diagnostic biomarkers, the first key point is standard isolation and characterization of sEVs

Therefore, given the pleiotropic functions of -KG, we aimed to explore whether and how -KG potentially regulates energy sensing and metabolic adaptation of cancer cells to energy stress

Concurrently, ROS oxidatively modify tau protein, enhancing its hyperphosphorylation and subsequent aggregation into neurofibrillary tangles, thereby disrupting microtubule stability and axonal transport [334]