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When combined with a healthy diet and exercise, they can significantly enhance your results, but they dont cause weight loss on their own

While optimizing those nutrient inputs and exercise can help support healthy NAD+ levels, for most adults, this probably wont be enough

"Benign Prostatic Hyperplasia: Surgical Therapy & New Technology II (MP09)"

View source Current Pharmaceutical Design 2016 PMID 27138887 Sikiric P et al

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That paper reported no genotoxic findings across an Ames test, a chromosomal aberration assay, and a bone micronucleus assay in rodent models