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From physiology to pharmacology Our discovery of GLP-1 as a satiety hormone was patented in collaboration with the pharmaceutical company Novo Nordisk A/S in November 1996 [7] (I receive no royalty or other payments)

Compare this to the side effect profile of pharmaceutical GLP-1 medications , where nausea affects 40 to 50 percent of users, vomiting occurs in 20 to 30 percent, and constipation is reported by a significant proportion of people throughout treatment

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Adults: prospective cohort study of the national health and nutrition examination survey 2003-2018