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Although more research is needed to fully elucidate this relationship, the findings are promising

10.1016/j.bbi.2018.02.016 376 QuL.LiuF.FangY.WangL.ChenH.YangQ.et al

419,420,421,422 Loss of astrocytes leads to an overall decrease in neuroprotection and affects neurotransmission

For example, rats treated with the benzodiazepine antagonist flumazenil along with a benzodiazepine do not develop tolerance but still apparently experience an anxiolytic effect

Early cognitive impairment during aging is mechanistically connected with elevated bioenergetic defects and a more oxidant state in the mitochondrial environment [85]

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