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Given the essential role of astrocytes in clearing and detoxifying many substances and the changes in astrocyte functions that such substances can evoke, it is interesting to consider (and worthy of more extensive investigation) that chronic exposure to trace amounts of such substances might act as risk factors and comorbidities in a variety of CNS neurodegenerative conditions

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The bodys healing process may lead to sensations that can be mistaken for the original pain, but these are typically less severe and gradually diminish over time