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Both routes are generally well-tolerated

Biochem Pharmacol 86(9):13011310 Podyacheva EY, Kushnareva EA, Karpov AA, Toropova YG (2021) Analysis of models of doxorubicin-induced cardiomyopathy in rats and mice

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The presence of pouches in the large intestine is known as diverticular disease or diverticulosis, but when the pouches are inflamed, it becomes diverticulitis and poses an issue