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Khlevner J, Park Y, Margolis KG

The documented considerations include mild water retention (a class effect of raising GH), injection-site reactions, occasional headache or lightheadedness, and most importantly for long-term thinking IGF-1 and sustained-GH-elevation considerations, which are why cycling with breaks is favored over indefinite use

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Human AEC (hAEC) exerted an inhibitor effect on proliferation of naive CD4 + T cells and production of Th1 and Th17 cytokines, while induced production of Th2 cytokines and augmented differentiation of Tregs and production of TGF-1 and IL-10 (73, 74)

Compound-level reports from animal studies and small human exposure data describe low acute toxicity

However, beyond the commonly discussed digestive side effects, many patients report experiencing lightheadedness, dizziness, or feeling faintsymptoms that can significantly impact daily life