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Insulin like growth factor-1 (IGF-1) is present in bone matrix, which even localizes to mandibular condylar cartilage and expedites growth process under growth hormone and androgens 16,17

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Lancet Diabetes Endocrinol 13:221262 Rudnicka E, Suchta K, Grymowicz M, Calik-Ksepka A, Smolarczyk K, Duszewska AM, Smolarczyk R, Meczekalski B (2021) Chronic low grade inflammation in pathogenesis of PCOS

Unlike DHT blockers or vasodilators, copper peptides operate through a nourishment pathway no hormonal interference, no immune suppression