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A: DSIP is typically used in rodent models, neuronal and glial cell cultures, and molecular signaling assays
Calcitriol can affect neuroplasticity, apoptosis, and gene expression (such as neurotransmitters, neurotrophic, and synaptic proteins) (102)
however, the generally accepted model is that after ligand binding to LRP1, the ligandLRP1 complex is taken up into early endosomes ( +/+ HepG2 cells, ICC data show that HPX moves into two populations of endosomes (Figure 4)
In ischemiareperfusion injury models, it preserved vascular integrity and reduced inflammation in organs such as liver, kidney, and lungslikely via endothelial stabilization through the nitric-oxide system
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studies in cultured mouse kidney cells
