When combined, testosterone protects and builds muscle while GLP-1 medications drive fat loss
Inhibition of COX-2 by NSAIDs blocks PG production at sites of inflammation, whereas inhibition of COX-1 in other tissues (platelets and the gastroduodenal mucosa) leads to common adverse effects of NSAIDs, such as bleeding and gastrointestinal ulceration (6)
Nausea, mild abdominal discomfort, and occasional vomiting are frequent, usually mild to moderate, and typically improve over several weeks as the body adjusts to the medication
Cell Commun Signal (2012) 10(1):21.10.1186/1478-811X-10-21 123 Flores-MoralesAGreenhalghCJNorstedtGRico-BautistaE
On average, clinical trials have demonstrated that patients can achieve a weight loss of anywhere from 15% to over 20% of their initial body weight over a period of 68 to 72 weeks
Table 2 Summary of Metformin Indications