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System XC- plays a significant role by transporting cysteine into cells as cystine, which is then reduced back to cysteine by reducing agents like glutathione (GSH) (Parker et al

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Certain populations, including the elderly and pregnant women, may also experience increased rates of constipation due to hormonal changes and decreased mobility

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GHS-R1a is also expressed in hypothalamus, hippocampus, cardiac tissue, pancreas, immune cells, adipose, and bone