In the ACHIEVE-1 study, a 36 mg dose resulted in a reduction in HbA1c of 1.31.6% from a baseline of 8.0%, and an average weight loss of 7.9% (approximately 16.0 lbs) over 40 weeks
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Water, Dipropylene Glycol, Galactomyces Ferment Filtrate(50,029 ppm), Glycerin, Methylpropanediol, Glycereth-26, Niacinamide, Glyceryl Glucoside, Glyceryl Polymethacrylate, Erythritol, Polyglyceryl-10 Laurate, Hydroxyacetophenone, 1,2-Hexanediol, Carbomer, Caprylyl Glycol, Arginine, Hydrolyzed Jojoba Esters, Xanthan Gum, Adenosine, Glucose, Ethylhexylglycerin, Butylene Glycol, Citric Acid, Ascorbic Acid, Polyquaternium -51, Panthenol, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Diethylhexyl Sodium Sulfosuccinate, Sodium Citrate, Lavandula Angustifolia (Lavender) Oil, Glutathione(10.89 ppm), Sodium Hyaluronate, Dipotassium Glycyrrhizate, Oryza Sativa (Rice) Extract, Pyrus Malus [Apple] Fruit Extract, Saccharide Isomerate, Hydrogenated Lecithin, Pantolactone, Maltodextrin, Brassica Oleracea Italica (Broccoli) Extract, Hydrolyzed Vegetable Protein, Prunus Serrulata Flower Extract, Nelumbo Nucifera Flower Extract, Lilium Tigrin um Extract, Copper Tripeptide-1, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Pentylene Glycol, Sodium Acetylated Hyaluronate, Disodium EDTA, Limonene, Linalool

The modest impact of transcription factor Nrf2 on the course of disease in an ALS animal model
Neurology 51:583586 Beauverd M, Mitchell JD, Wokke JH, Borasio GD (2012) Recombinant human insulin-like growth factor I (rhIGF-I) for the treatment of amyotrophic lateral sclerosis/motor neuron disease