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LDL cholesterol remains a primary clinical marker, while oxidized LDL is generally considered a specialty biomarker that may add context in selected cases
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Blood 86(10):337a, 1995
In contrast, the intrinsic pathway arises from intracellular disturbances, particularly the suppression or inactivation of antioxidant systems such as GPX4, resulting in unchecked lipid peroxidation
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