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Robert Kushner: Well, the BMI classifications, the cut points you mentioned, have actually now been removed by the FDA for semaglutide and the other drug called tirzepatide, the two major drugs on the market

Tirzepatide also acts on the GIP receptor, potentially providing greater benefits for blood sugar control and weight reduction compared to Ozempic

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Retrospective analysis of long-term adherence to and persistence with DPP-4 inhibitors in US adults with type 2 diabetes mellitus

They soon discovered that GLP-1 receptors are found on immune cells, not just in the pancreas and gastrointestinal tract, suggesting that drugs from this group may directly affect mechanisms responsible for the development of chronic inflammation

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