Science 366:10131021 Li B, Cao Y, Meng G et al (2019a) Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway
For example, the inhalant and oral solution forms have a mucolytic effect, and are used to relieve obstructions in bronchial diseases and in tracheotomy procedures
Translation into clinical applications remains an unresolved question
Lactate shuttle The lactate produced by astrocytes can be exported and used as an alternative energy substrate by neurons (Mchler et al., 2016), supporting their survival under pathological conditions (Inverse Warburg effect)
A sourdough starter consists of lactic acid bacteria, whose contribution to enhanced folate levels, in contrast to yeast, is negligible 372,418,422,423,424
A recent review on glutathione highlights the importance of innovative analogue approaches to overcome poor oral bioavailability, ensuring more effective systemic antioxidant support