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In contrast, the vehicle-treated MCAO group showed no significant change in fall latency over time
Accumulated cellular iron generates cytotoxic hydroxyl radicals (OH) via the Fenton reaction
(2) Extracellular vesicles (EVs)-mediated metastatic reprogramming through cargo remodeling (e.g., pro-inflammatory proteins) and dysregulation of oncogenic miRNAs
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Establishing it as a multi-system repair peptide whose actin dynamics mechanism operates across tissue types including the central nervous system
Cell 161 , 10351045 (2015)
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