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The drug is known as a triple-agonist, meaning it targets three different receptors in the brain and throughout the body
Utilization and cost of non-insulin glucose-lowering drugs in Australia from 2013 to 2023
Although the actions of GLP-1 on the beta-cell are preserved yet modestly diminished in T2DM, the diabetic alpha-cell retains near normal responsivity to low dose GLP-1 infusion, with inhibition of glucagon secretion seen to a similar extent in diabetic vs
Y., Yazici, D., Pizzagalli, D
Moreover, patients with acromegaly treated with either GH-receptor antagonists or somatostatin analogues represent a peculiar setting that need to be studied in depth to define safety and efficacy of both drug classes and their interaction with the GH/IGF-1 axis
Grill HJ, Hayes MR (2012)
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