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Abstract Background Gallstones represent a significant global health challenge, impacting both the healthcare system and the broader socio-economic landscape

The point is not to use those doses but to illustrate the wide safety margin

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These nanoparticles can be engineered to specifically target cardiac, vascular, or neuronal mitochondria, enabling more efficient and targeted delivery of therapeutic agents

The key factor is its rapid absorption into the bloodstream, which is similar across common SubQ sites