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"For anxiety and depression that co-occur with diabetes and obesity, semaglutide and, to a lesser extent, liraglutide might be useful, dually effective therapeutic options," the authors from University of Eastern Finland, Karolinska Institutet in Stockholm and Griffith University in Australia wrote

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This dual action not only suppresses appetite and reduces calorie intake but also improves glucose control and energy utilization more effectively than medications that target only one of these pathways

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In our model, cells primed with Exendin-4 presented higher glycolytic rates when returned to culture media in the absence of GLP-1R stimulation