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Handling: Wear appropriate personal protective equipment (PPE) including gloves and safety eyewear

Key supplements include methylfolate, methylcobalamin (B12), betaine (TMG), and comprehensive electrolytes with potassium and magnesium

The response curves show that most participants were still losing weight at week 68, suggesting that longer treatment durations might produce even greater reductions

Second, the hyperpigmentation risk note directly shapes our protocol for Fitzpatrick IV-V patients, where we apply more conservative needle depths and timing

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