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Discovery of caffeoylisocitric acid as a Keap1-dependent Nrf2 activator and its effects in mesangial cells under high glucose

In 2023, the FDA launched an investigation after GLP-1 agonist users started reporting thoughts of suicide as of January 2024, it hadnt found anything to confirm the connection, but it also said it couldnt yet rule it out, meaning its possible the drugs could cause mental health issues for some people, rather than treating or preventing them

Combines appetite suppression with increased metabolic rate from glucagon agonism

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Embora seja um benefcio para algumas pessoas, a perda de peso significativa pode ser um risco para outras, especialmente aquelas que no precisam ou no desejam perder peso

Less common, more serious side effects can also occur, including pancreatitis, gallbladder disease, or worsening of diabetic eye disease