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Add-on to 1-3 oral anti-hyperglycemic agents (metformin, sulfonylurea, or SGLT-2 inhibitor) SURPASS-4 (NCT03730662) was a 104-week open-label trial (52-week primary endpoint) that randomized 2002 adult patients with type 2 diabetes mellitus with increased cardiovascular risk to subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or insulin glargine 100 units/mL once daily (1:1:1:3 ratio) on a background of metformin (95%) and/or sulfonylureas (54%) and/or SGLT2 inhibitors (25%)

JAMA, 322(13), 1271-1282

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L., Bell, S., & Liao, W

But since it is a version of Selank with modifications aimed at improving its stability rather than changing its effects, it is reasonable to infer that N-Acetyl Selank Amidate may have similar mechanisms to its parent molecule

Limitations of the study The findings of this study could be considered with a few limitations