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In high-fat diet (HFD) mouse models, subcutaneous dosing at approximately 0.3, 3, and 30 nmol/kg/day over 21 days produced dose-dependent body weight reductions
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Nevertheless, it's essential to acknowledge the considerable inter-individual variability in B12 levels, complicating the establishment of a universal deficiency threshold due to a lack of standardization (Taher et al
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doi: 10.1002/JCP.10022 56 NomuraKImaiHKoumuraTKobayashiTNakagawaY
