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Once volume is reduced, the skin envelope may no longer fit the underlying shape

Patients may want to ask How often follow up visits occur What markers are tracked over time How decisions about dose changes or continuation are made Professional obesity care guidance consistently emphasizes longitudinal monitoring rather than episodic treatment

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GLP-1 has a natriuretic effect in the proximal renal tubules, the beneficial effects of GLP-1 and GLP-1RA may be related to the regulation of the RAAS (177)