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In trials focused on people with type 2 diabetes, a population already at elevated heart risk, GLP-1s consistently reduced serious cardiovascular events by 1226% depending on the drug and population, with strong results for stroke prevention

BM, AH, and AK participated equally in searching the data and writing of the review

The compound promotes collagen production, enhances skin elasticity, and accelerates tissue repair

Some lock patients into 3-month commitments

In the STEP clinical trials for semaglutide and the SURMOUNT trials for tirzepatide [8,9]

These interactions suggest that the gut microbiota not only mediates the metabolic benefits of GLP-1 RAs but also may modulate individual responses to treatment [83]