The Nuance of Action: Systemic vs
Dehydration: the main risk for people with CKD In October 2024, the MHRA issued a Drug Safety Update warning that gastrointestinal side effects from GLP-1 receptor agonists can lead to dehydration and, in some cases, kidney damage requiring hospitalisation
Recommendation: Routine drug withdrawal is not justified by the data
PlexusDx patients who remain concerned should discuss adjustments with their provider, as dose or formulation changes sometimes help
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Acta 126 , 4151 (1982)
