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Clinical trial data shows that at the 2.5 mg starting dose, gastrointestinal adverse events are significantly lower than at therapeutic doses of 10 or 15 mg

The retrospective study of intra-articular knee injections noted no significant adverse events in 16 participants

Dietary factors also play important roles

To inject 1mg, you would draw 0.2ml (or 20 units on a standard insulin syringe marked in units)