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Depression: A meta-analysis of 5 RCTs (n=574) found that NAC significantly improved depressive symptoms, particularly in individuals with high baseline symptom severity (Fernandes et al., J Clin Psychiatry, 2016) [73]

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The specific target, anti-tumor effect, and clinical progress of these inhibitors targeting NADPH metabolism are also summarized in Tables 1 and 2

However, there is an obvious difference in the CTD structure, which is highly conserved in FSP1 proteins from different species (Supplementary Fig

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