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[1] Tirzepatide should be used with caution in patients with severe gastrointestinal disease, including severe gastroparesis

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Rather than focusing only on the number on the scale during your first week, look for other positive changeslike increased energy, better sleep, or improved moodthat show your body is responding to your personalized plan

Also, previous reports have shown that acute treatment with MC4R agonists results in increased repetitive behavior and increased anxiety-like behavior in both the presence and absence of psychological stress [43, 44, 45]

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