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However, its long-term safety and possible unpleasant adverse effects in humans are not fully understood

Moreover, HIF-1 plays a crucial role in promoting the activation of classical M1 macrophages and regulating phosphofructokinase activity, thereby impacting the expression of inflammation-related genes [50]

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The knee joints were incised using the medial parapatellar approach, and the patella was moved laterally to expose the femoral trochlear articular surface