[2] The medication works by enhancing glucose-dependent insulin secretion, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways
Second, to test the assumption of exchangeability and exclusion restrictions, we searched on the PhenoScanner website ( and ensured that the genetic predictors were not directly associated with MASLD and known confounders (Supplementary Table 7)
Each batch is third-party tested for purity by an independent analytical laboratory
An oral GLP-1 drug, Foundayo, is new to the market
The Bridge and the negotiation program are separate
GLP-1RAs are well-established for managing T2D and obesity (61,73,74), and exhibit emerging antitumor potential in related cancers, such as colorectal and endometrial cancers (75,76)