Summary Certificate of Analysis (COA) Resource Characteristics How is Epithalon Used in Research
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It is believed that oxidative stress (cell damage caused by free radicals), chronic neuroinflammatory processes, disruptions in neurogenesis and synaptogenesis, as well as an imbalance in the level of neurotransmitters play a key role in the pathology of anxiety and depressive disorders (Gold et al
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Structure-activity relationship studies have highlighted that the two phenyl rings connected by a C-7 linker with keto-enol functionality are crucial for curcumins biological activity (87)
As an additional control, growth inhibition assays were conducted on the antimalaria compounds artemisinin and chloroquine: the IC 50 values obtained (12 nM and 22 nM, respectively) are comparable to previously published results ( Supplementary Figure 6 )
