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Somatic mutations cause amino acid substitutions
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The colonies were inoculated into 200 L YP20D medium containing 14 mM of acrolein, and cultivated at 30 C and 900 rpm for 48 h
Several factors have been hypothesized though none have demonstrated definitive causation, including tobacco and alcohol exposure through chronic smoking, chewing, or excessive consumption, which have been potentially implicated in oral cancer broadly though the specific relationship with oral melanoma remains unclear [7]
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