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Gastroenterology 132 , 21312157, doi:10.1053/j.gastro.2007.03.054 (2007)
This protective effect persisted in Glp1r Tie2/ mice, suggesting that the expression of immune cell or endothelial cell GLP-1Rs is not essential for this action
On the other hand, in HF patients, cardiac energy metabolism is shifted from fatty acid oxidation to glucose, and carnitine insufficiency in the failing myocardium is caused by the leakage of carnitine through damaged cardiomyocyte membranes [4]
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Thats why when a scientist discovers a particular protein thats important in a cellular process or disease, one of the first things they will do is examine its molecular interactions