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Findings from two key clinical trials have demonstrated the efficacy and safety of an oral formulation of the glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide for the treatment of obesity and type 2 diabetes

The first protein shown to be modified by succination was glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

Managing Side Effects Gastrointestinal symptoms occur frequently during initial treatment and dose escalations

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