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EGCG simply slows the clearance of naturally circulating norepinephrine a far gentler mechanism that elevates metabolic rate without triggering the cardiovascular stress response associated with stimulants

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Studies in elderly human populations and aged primates observed measurable changes in nocturnal melatonin levels and circadian melatonin rhythm patterns in subjects receiving the AEDG peptide or epithalamin (6, 7)

Most patients experience these effects as temporary and manageable, though individual responses vary

The drugs known to be useful for the treatment of E