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We found downregulation of p53 and its downstream target GADD45A, and upregulation of the E3 ubiquitin ligase RCHY1, which targets p53 for degradation 52 , in BWS hepatocytes relative to control at day 15 (Supplementary Fig

[DOI] [PubMed] [Google Scholar] 37.Baldwin A.S

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I haven't had an ANA done, which I will discuss with the rheumatologist

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