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The short answer: probiotics are generally safe alongside semaglutide, but timing and strain selection matter for optimal outcomes

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PASS guidance is evolving and staying aligned with these developments is critical

In contrast, Barrea et al

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Although the findings in the CANVAS trial showed a higher risk of amputation when taking canafliglozin compared to placebo [92], no significant difference in the risk of this complication was observed in the CREDENCE study [88]