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The sequences of primers used in the analysis were provided in Table S1

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Lastly, health-system integration is complicated by uncertainties in reimbursement and regulatory classification (e.g., whether device, drug-device combination, or medicinal product), and postpones large, late-phase clinical trials

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Owing to its proven efficacy and safety, 406 the FDA expanded its indication in 2023 to include children aged 511 years with HoFH, marking an important milestone in the treatment of pediatric lipid disorders

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