[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Holloway P.M., Gillespie S., Becker F., Vital S.A., Nguyen V., Alexander J.S., Evans P.C., Gavins F.N.E
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In lupus prone MPL/lpr mice, administration of bortezomib was found effective in preventing and more importantly treating established disease ( Although proteasome inhibition is attractive, the main concern for adding these seemingly potent medications in the SLE therapeutic armamentarium remains the severe toxicity associated with their chronic use